ABOUT THE EVIDENCE SYNTHESIS TSD SERIES

A series of seven TSDs have been produced in the area of Evidence Synthesis. These are:

TSD 1

Introduction to evidence synthesis for decision making


TSD 2

A general linear modelling framework for pair-wise and network meta-analysis of randomised controlled trials (last updated April 2014)
WinBUGS system(.odc) files (last updated March 2013)


TSD 3

Heterogeneity: subgroups, meta-regression, bias and bias-adjustment
WinBUGS system(.odc) files


TSD 4

Inconsistency in networks of evidence based on randomised controlled trials (last updated April 2014)
WinBUGS system
(.odc) files (last updated March 2013)


TSD 5

Evidence synthesis in the baseline natural history model 
WinBUGS system(.odc) files

TSD 6

Embedding evidence synthesis in probabilistic cost effectiveness analysis: software choices

TSD 7

Evidence synthesis of treatment efficacy in decision making: a reviewer's checklist
This report refers to a checklist table, which can be downloaded in Word version here

TSDs 1 to 7 have been published as a series in Medical Decision Making (July 2013)

The intention behind the TSDs is not to be prescriptive, but rather to explain the requirements for evidence syntheses set out in the 2008 Methods Guide and to provide guidance on methods that meet these requirements.

TSDs 2, 3, 4 and 5 include an extensive set of worked examples of analyses using Bayesian Markov chain Monte Carlo methods, using WinBUGS. The WinBUGS code should not be copied and pasted from the text; users are instead advised to download the WinBUGS system (.odc) files.

When all seven documents have been completed, those already on the website will be updated in order to harmonise and complete the cross-referencing. Instructions for citing these documents can be found on page 3 of each TSD.

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