Welcome to the NICE Decision Support Unit

The latest news from the DSU



DSU report: Comparing the EQ-5D-5L and 3L: What are the Implications for Cost-Effectiveness Estimates? (March 2017)

Real World Data (RWD)
DSU report: The use of real world data for the estimation of treatment effects in NICE decision making (June 2016, updated December 2016)

Population-adjusted indirect comparisons (MAIC and STC) TSD 
TSD18: Methods for population-adjusted indirect comparisons in submissions to NICE (December 2016)

TSD2 - A general linear modelling framework for pair-wise and network meta-analysis of randomised controlled trials
Update to Evidence Synthesis Technical Support Document 2 - available from September 2016 - coding revised for Example 6.

Degarelix for prostate cancer
DSU report: Spinal cord compression associated with hormonal therapy in men with hormone-dependent metastatic prostate cancer: A systematic review and economic assessment (made available online June 2015)
Guidance published August 2016

Managed Entry Agreements (MEA)
DSU report: Framework for analysing risk in Health Technology Assessments and its application to Managed Entry Agreements (January 2016)

RA review
DSU report: Progression of disease in people with Rheumatoid Arthritis treated with non biologic therapies (made available online June 2015)

Observational data TSD
TSD17: The use of observational data to inform estimates of treatment effectiveness in technology appraisal: Methods for comparative individual patient data (May 2015) 

Econometric Mapping of Utilities - Stata command
Publication: ALDVMM: A command for fitting Adjusted Limited Dependent Variable Mixture Models to EQ-5D (made available online May 2015)

End of Life
Publication: Valuing health at the end of life: a stated preference discrete choice experiment (Jan 2015)

Not cost-effective at zero price
Assessing technologies that are not cost-effective at a zero price (made available online November 2014)

Mapping of EQ-5D
Publication: A comparison of direct and indirect methods for the estimation of health utilities from clinical outcomes (Oct 2014)


The DSU is currently involved in work in the following areas:

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